By National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Nuclear and Radiation Studies Board, Committee on State of the Science of Nuclear Medicine
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Extra resources for Advancing Nuclear Medicine Through Innovation
It is also used to detect residual cancer and to monitor the reduction in tumor that it can be treated with a minimally invasive and, often, image-guided approach. The most exciting area in imaging today and going forward is molecular imaging through various imaging technologies from the laboratory setting to clinical research and practice. Molecular imaging has become a scientific discipline in its own right, as well as a growing practice in medicine. MRI and optical imaging, as well as nuclear medicine imaging, can be used for molecular targeting.
All of these probes can be chemically attached or encapsulated to target specific tissue receptor sites or may be attached to a moiety that preferentially accumulates in a region of interest. Nuclear photons, unlike optical ones, can escape from the body and thus can be used for more deeply seated targets (Weissleder 2006). It is therefore likely that nuclear 28 ADVANCING NUCLEAR MEDICINE THROUGH INNOVATION medicine procedures can be developed to provide the precise information required to pinpoint the location of subclinical disease for minimally invasive treatment.
Sidebar 2-9, fig 2 37 NUCLEAR MEDICINE In PET, there are four types of coincidence events: true, scattered, random, and multiple. Figure 3 illustrates the first three. A coincidence event is assigned to a line of response (LOR). In this way, positional information is gained from the radiation that is detected. FIGURE 3 Types of coincidences. Sidebar2-9, fig 3 Time-of-flight means that for each annihilation event the precise time that each of the coincident photons is detected is noted and the difference in arrival time is calculated.